Using Hydrogel Beads as a Blood Model in Optical Coherence Tomography

Abstract Optical Coherence Tomography (OCT) is a standard imaging procedure in ophthalmology. OCT Angiography promising extension, allowing for fast and non-invasive of the retinal vasculature analyzing multiple scans at same place. Local variance examined highlighted. Despite its introduction clinic, unanswered questions remain when it comes to signal generation. Multiphase fluids like intralipid, milk-water solutions human blood cells were applied phantom studies shedding light on some mechanisms. The use hydrogel beads allows generation alternative models Angiography. Beads produced Hannover, their size was measured long term stability assessed. Then, shipped Karlsruhe, where resulted first insights. acts as diffusion barrier, which enables clear distinction bead fluid scattering particles added. Further on, medium below showed increased intensity. We conclude that inside structure shows enhanced transmission compared plasma substitute with dissolved TiO2 surrounding it. found clumped deformed after shipping, an issue be addressed further investigations. Nevertheless, are model investigations, offering tunable optical parameters within solution.